DNA SEQUENCING – NGS (Somatic SNVs and indels + matched germline sample)

Product Code: NGS(vSOMATICMATCHED)-25

From £1115.00

Registration closed: 28/02/2025

Applicable to any lab using requiring a matched normal control germline sample as part of their somatic NGS testing process. Pilot EQA.

Target/Genes:

Participating laboratories can use any NGS strategy to participate (single gene, panel testing, whole exome sequencing or whole genome sequencing). This EQA scheme includes a matched germline normal sample. The scheme will assess all single nucleotide variants and indels 50bp or less in size.

Technology:

NGS, Whole exome sequencing, Whole genome sequencing

Language:

Not applicable

Sample Type:

gDNA (from FFPE or fresh frozen sample)

Accredited:

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EQA Assessment

This EQA scheme is NOT suitable for somatic NGS workflows
that DO NOT require a matched normal control sample. Please see our DNA
SEQUENCING – NGS (Somatic – no matched germline sample) EQA scheme.

Sample Details

One mock clinical case with matching tumour DNA and germline DNA samples will be provided. Approximately 1-2µg DNA per sample is provided depending on testing strategy. Complete information will be available in the scheme instructions. Laboratories will be contacted prior to sample dispatch to obtain testing strategy for sample requirements.

EQA Results

Participants will receive a comprehensive individual data quality report and a variant consensus analysis report for each submission. A comprehensive summary scheme report is provided including additional information from the cohort of participants including geographical spread, methodologies employed, common errors, learning points and scheme statistics allowing participants to benchmark their results.

Each laboratory will also receive a single certificate listing all EQAs participated in with performance result for each year.

Participation Information

No restrictions on number of participants. Open to laboratories from ALL countries (note: some restrictions may apply*)

*Sanctions, delivery network exceptions, restrictions on importation etc.

How it works

Register

Enrol before the closing date
EMQN ships EQA samples or digital cases

Test & submit results

Analyse samples in your routine workflow
Upload results via QA Manager

Review & get certified

EMQN benchmarks your data
Receive final report & Certificate of Participation

Enquire about this scheme

Contact Information

office@emqn.org

Phone

+44 161 757 1591

Featured EQA Schemes

Genomic and Inherited Disorders

Charcot-Marie-Tooth disease / Hereditary Neuropathy with liability for Pressure Palsies (CMT/HNPP) (PMP22 and optional gene panel testing for other CMT-associated genes).

Product Code: NGS(vSOMATICMATCHED)-25

From £445.00

Deadline to order: 30/11/2025

Applicable to all labs undertaking molecular genetic testing for these disorders.
- Language: English, German
- Accredited: Yes
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Pre-analytical processes

cfDNA extraction from plasma (Round 2)

Product Code: NGS(vSOMATICMATCHED)-25

Free

Registration closed: 31/03/2025

Applicable for all labs extracting cfDNA from plasma. Two rounds of EQA per year – purchase each separately.
This EQA will be distributed in SEPTEMBER 2025.
- Language: English
- Accredited: No
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Genomic and Inherited Disorders

Congenital Adrenal Hyperplasia (CAH)

Product Code: NGS(vSOMATICMATCHED)-25

From £445.00

Registration closed: 30/11/2024

Applicable to all labs undertaking molecular genetic testing for this disorder.
- Language: English, German
- Accredited: Yes
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Molecular Pathology

Colorectal cancer [Tissue]

Product Code: NGS(vSOMATICMATCHED)-25

From £630.00

Registration closed: 28/02/2025

Applicable to all labs undertaking molecular testing for this cancer using FFPE tissue.
- Language: English
- Accredited: Yes
Register Interest More Information
Pre-analytical processes

cfDNA extraction from plasma (Round 1)

Product Code: NGS(vSOMATICMATCHED)-25

Free

Registration closed: 28/02/2025

Applicable for all labs extracting cfDNA from plasma. Two rounds of EQA per year – purchase each separately.
This EQA will be distributed in MARCH 2025.
- Language: English
- Accredited: No
Register Interest More Information
Genomic and Inherited Disorders

Cardiac Genetics Gene Panel: Hypertrophic Cardiomyopathies

Product Code: NGS(vSOMATICMATCHED)-25

From £445.00

Registration closed: 30/11/2024

Applicable to labs that undertake NGS-based testing for this group of disorders (including targeted panel testing/ virtual panel /clinical exome / WES / WGS)
- Language: English
- Accredited: Yes
Register Interest More Information
Molecular Pathology

Breast cancer (ESR1 cfDNA testing) [Plasma]

Product Code: NGS(vSOMATICMATCHED)-25

From £285.00

Registration closed: 28/02/2025

Applicable to labs undertaking molecular testing of the ESR1 gene in cfDNA
- Language: English
- Accredited: No
Register Interest More Information
Genomic and Inherited Disorders

Cardiac Genetics Gene Panel: Arrhythmias

Product Code: NGS(vSOMATICMATCHED)-25

From £445.00

Registration closed: 30/11/2024

Applicable to labs that undertake NGS-based testing for this group of disorders (including targeted panel testing/ virtual panel /clinical exome / WES / WGS)
- Language: English, French
- Accredited: Yes
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Molecular Pathology

Breast cancer (AKT pathway gene testing (PIK3CA, AKT1, PTEN) [Tissue]

Product Code: NGS(vSOMATICMATCHED)-25

From £285.00

Registration closed: 28/02/2025

Applicable to labs undertaking molecular testing of the PIK3CA, AKT1 and PTEN genes in this type of cancer.
- Language: English
- Accredited: Yes
Register Interest More Information

DNA SEQUENCING – NGS (Somatic SNVs and indels + matched germline sample)

Target/Genes:

Technology:

Language:

Sample Type:

Accredited:

EQA Assessment

Sample Details

EQA Results

Participation Information

How it works

Register

Test & submit results

Review & get certified

Enquire about this scheme

Contact Information

Featured EQA Schemes

Charcot-Marie-Tooth disease / Hereditary Neuropathy with liability for Pressure Palsies (CMT/HNPP) (PMP22 and optional gene panel testing for other CMT-associated genes).

cfDNA extraction from plasma (Round 2)

Congenital Adrenal Hyperplasia (CAH)

Colorectal cancer [Tissue]

cfDNA extraction from plasma (Round 1)

Cardiac Genetics Gene Panel: Hypertrophic Cardiomyopathies

Breast cancer (ESR1 cfDNA testing) [Plasma]

Cardiac Genetics Gene Panel: Arrhythmias

Breast cancer (AKT pathway gene testing (PIK3CA, AKT1, PTEN) [Tissue]

Register Interest